Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0008 enzyme activity assay fructan Bacteroides thetaiotaomicron 28103254
A Highly Active Endo-Levanase BT1760 of a Dominant Mammalian Gut Commensal Bacteroides thetaiotaomicron Cleaves Not Only Various Bacterial Levans, but Also Levan of Timothy Grass. PLoS One. 2017 Jan 19;12(1):e0169989. doi: 10.1371/journal.pone.0169989. eCollection 2017.
2017 degradation 12 2 GH32, GH32, GH32
PUL0026 qPCR, Western Blot, RNA-Seq, enzyme activity assay ribose Bacteroides thetaiotaomicron 31901520
A Ribose-Scavenging System Confers Colonization Fitness on the Human Gut Symbiont Bacteroides thetaiotaomicron in a Diet-Specific Manner. Cell Host Microbe. 2020 Jan 8;27(1):79-92.e9. doi: 10.1016/j.chom.2019.11.009. Epub 2019 Dec 31.
2020 Jan 8 degradation 8 1 GH0, GH35
PUL0115 recombinant protein expression, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 7 7 GH33, GH20, GH2, GH20, GH20, GH2
PUL0116 recombinant protein expression, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 2 1 GH20
PUL0117 recombinant protein expression, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 22 4 GH92, GH130, GH163, GH20
PUL0119 recombinant protein expression, RNA-Seq, differential gene expression N-glycan Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 2 1 CBM32, GH29
PUL0120 recombinant protein expression, RNA-Seq, differential gene expression N-glycan, mucin Bacteroides thetaiotaomicron 31160824
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 6 2 CBM14, GH18
PUL0145 enzyme activity assay glycosaminoglycan, chondroitin sulfate Bacteroides thetaiotaomicron 30262663
The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29. J Biol Chem. 2018 Nov 16;293(46):17906-17916. doi: 10.1074/jbc.RA118.004510. Epub 2018 Sep 27.
2018 Nov 16 degradation 27 5 PL8, PL8_2, PL29, GH2, GH88, PL8_2
PUL0161 mass spectrometry, sequence homology analysis alpha-mannan Bacteroides thetaiotaomicron 30246424
Alpha- and beta-mannan utilization by marine Bacteroidetes. Environ Microbiol. 2018 Nov;20(11):4127-4140. doi: 10.1111/1462-2920.14414. Epub 2018 Oct 16.
2018 Nov degradation 26 6 GH97, GH67, GH76, GH92, GH76, GH125
PUL0162 mass spectrometry, sequence homology analysis alpha-mannan Bacteroides thetaiotaomicron 30246424
Alpha- and beta-mannan utilization by marine Bacteroidetes. Environ Microbiol. 2018 Nov;20(11):4127-4140. doi: 10.1111/1462-2920.14414. Epub 2018 Oct 16.
2018 Nov degradation 13 2 GH92, GH99
PUL0163 mass spectrometry, sequence homology analysis alpha-mannan Bacteroides thetaiotaomicron 30246424
Alpha- and beta-mannan utilization by marine Bacteroidetes. Environ Microbiol. 2018 Nov;20(11):4127-4140. doi: 10.1111/1462-2920.14414. Epub 2018 Oct 16.
2018 Nov degradation 21 7 GH92, GH38, CBM32, GT32, GT32, GH130, GH125, GH76, GH92, GH76
PUL0203 qPCR, thin layer chromatography, substrate binding assay exopolysaccharide Bacteroides thetaiotaomicron 25841008
Differential Metabolism of Exopolysaccharides from Probiotic Lactobacilli by the Human Gut Symbiont Bacteroides thetaiotaomicron. Appl Environ Microbiol. 2015 Jun 15;81(12):3973-83. doi: 10.1128/AEM.00149-15. Epub 2015 Apr 3.
2015 Jun 15 degradation 7 3 GH32, GH32, GH32
PUL0204 qPCR, thin layer chromatography, substrate binding assay exopolysaccharide Bacteroides thetaiotaomicron 25841008
Differential Metabolism of Exopolysaccharides from Probiotic Lactobacilli by the Human Gut Symbiont Bacteroides thetaiotaomicron. Appl Environ Microbiol. 2015 Jun 15;81(12):3973-83. doi: 10.1128/AEM.00149-15. Epub 2015 Apr 3.
2015 Jun 15 degradation 7 3 GH97
PUL0205 qPCR, thin layer chromatography, substrate binding assay exopolysaccharide Bacteroides thetaiotaomicron 25841008
Differential Metabolism of Exopolysaccharides from Probiotic Lactobacilli by the Human Gut Symbiont Bacteroides thetaiotaomicron. Appl Environ Microbiol. 2015 Jun 15;81(12):3973-83. doi: 10.1128/AEM.00149-15. Epub 2015 Apr 3.
2015 Jun 15 degradation 6 3 GH31, GH31, GH66
PUL0223 enzyme specificity assay, enzyme activity assay N-glycan Bacteroides thetaiotaomicron 23943617
Discovery of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans. J Biol Chem. 2013 Sep 20;288(38):27366-27374. doi: 10.1074/jbc.M113.469080. Epub 2013 Aug 13.
2013 Sep 20 degradation 9 4 GH92, GH130, GH163
PUL0228 qRT-PCR, enzyme activity assay, high performance anion exchange chromatography arabinan Bacteroides thetaiotaomicron 22686399, 21339299
Prioritization of a plant polysaccharide over a mucus carbohydrate is enforced by a Bacteroides hybrid two-component system. The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases. Mol Microbiol. 2012 Aug;85(3):478-91. doi: 10.1111/j.1365-2958.2012.08123.x. Epub 2012 Jul 5. J Biol Chem. 2011 Apr 29;286(17):15483-95. doi: 10.1074/jbc.M110.215962. Epub 2011 Feb 21.
2012 Aug,2011 Apr 29 degradation 10 4 GH43, GH43_4, GH43_4, GH51, GH43_29
PUL0251 gene chips host glycan Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 7 1 CBM32
PUL0252 gene chips mucin, O-glycan Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 6 2 CBM32, GH29
PUL0253 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 32 13 GT2, GT2, GT101, GT0, GT2, GT2, GT4, GT4, GH27
PUL0254 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 28 2 GT4, GT4
PUL0255 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 16 4 GT2
PUL0256 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 19 2 GT4, GT4, GT94
PUL0257 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 15 5 GT4, GT2, GT4, GT2
PUL0258 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 10 4 GT2, GT2, GT2, GT25
PUL0260 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 14 1 GT4
PUL0261 gene chips capsule polysaccharide Bacteroides thetaiotaomicron 23996813
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 17 10 GT4, GT0, GT4, GT4, GT2, GT14, GT14, GT32, GT8, GT2, GT2
PUL0302 RT-qPCR, isothermal titration calorimetry, enzyme activity assay, gene deletion mutant and growth assay arabinan Bacteroides thetaiotaomicron 29255254
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol. 2018 Feb;3(2):210-219. doi: 10.1038/s41564-017-0079-1. Epub 2017 Dec 18.
2018 Feb degradation 22 6 GH51, GH146, GH43_4, GH43, GH43_4, GH51, GH43_29
PUL0304 RT-qPCR, isothermal titration calorimetry, enzyme activity assay, gene deletion mutant and growth assay galactan Bacteroides thetaiotaomicron 29255254
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol. 2018 Feb;3(2):210-219. doi: 10.1038/s41564-017-0079-1. Epub 2017 Dec 18.
2018 Feb degradation 7 2 GH2, GH53
PUL0305 RT-qPCR, isothermal titration calorimetry, enzyme activity assay, gene deletion mutant and growth assay homogalacturonan Bacteroides thetaiotaomicron 29255254
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol. 2018 Feb;3(2):210-219. doi: 10.1038/s41564-017-0079-1. Epub 2017 Dec 18.
2018 Feb degradation 17 7 GH105, CE8, CE4, CE8, CE12, PL1_2, PL1, CE8, PL1_2, PL1, CE8, PL1_2, GH28
PUL0325 RT-PCR, enzyme activity assay beta-glucan Bacteroides thetaiotaomicron 28461332
A Bacteroidetes locus dedicated to fungal 1,6-beta-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-beta-glucanase. J Biol Chem. 2017 Jun 23;292(25):10639-10650. doi: 10.1074/jbc.M117.787606. Epub 2017 May 1.
2017 Jun 23 degradation 6 2 GH30, GH30_3, GH3
PUL0350 microarray capsule polysaccharide Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 biosynthesis 21 3 GT4, GT2, GT4, GT2
PUL0352 microarray arabinan, xylan, levan, pectin, rhamnogalacturonan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 6 1 GH20
PUL0353 microarray, enzyme activity assay, strcutural analysis, clone and expression arabinan, xylan, levan, pectin, rhamnogalacturonan Bacteroides thetaiotaomicron 16968696, 32060313
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12. Nat Commun. 2020 Feb 14;11(1):899. doi: 10.1038/s41467-020-14754-7.
2006 Nov 24,2020 Feb 14 degradation 11 3 GH0, GH92, GH92
PUL0354 microarray lactose, host glycan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 8 3 GH93, GH0, GH43_31, GH43, GH43_31
PUL0355 microarray lactose, host glycan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 8 1 GH30_4, GH30, GH18
PUL0356 microarray lactose, host glycan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 9 1 GH18
PUL0357 microarray arabinan, xylan, levan, pectin, rhamnogalacturonan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 3 1 CBM32
PUL0358 microarray lactose, host glycan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 4 4 CBM32, GH35, GH43_19, GH43, GH43_9, GH43_19, GH43, GH51
PUL0359 microarray lactose, host glycan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 5 3 GH43_10, GH97, GH29
PUL0360 gene deletion mutant and growth assay lactose, host glycan Bacteroides thetaiotaomicron 16968696
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 6 2 GH2, GH53
PUL0375 microarray, qPCR alpha-mannan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 19 5 GH97, GH67, GH76, GH92, GH76, GH125
PUL0376 microarray, qPCR mucin, O-glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 9 2 GH16, GH18
PUL0377 microarray, qPCR glycosaminoglycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 27 3 PL8_2, PL8, PL29, GH2, GH88, PL8_2
PUL0378 microarray, qPCR alpha-mannan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 20 5 GH92, CBM32, GH38, GT32, GT32, GH130, GH125, GH76, GH92, GH76
PUL0379 microarray, qPCR alpha-mannan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 10 2 GH92, GH99
PUL0380 microarray, qPCR mucin, O-glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 12 4 GH0, GH92, GH92, GH92
PUL0382 microarray, qPCR mucin, O-glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 11 1 GH2, GH109
PUL0383 microarray, qPCR mucin, O-glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 5 1 GH89
PUL0384 microarray, qPCR glycosaminoglycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 12 3 PL15_2, PL15, PL12, PL12_2, GH88, PL12_2
PUL0463 microarray, qPCR host glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 13 2 GH89, CE2
PUL0464 microarray, qPCR host glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 16 6 GH33, GH20, GH2, GH20, GH20, GH2
PUL0465 microarray, qPCR mucin Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 8 2 GH18
PUL0467 microarray, qPCR host glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 14 5 GH29, CBM32, GH2, GH20, GH18
PUL0468 microarray, qPCR host glycan Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 47 2 GH43, GH43_26, GH76
PUL0469 microarray, qPCR starch Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 8 3 GH97
PUL0470 microarray, qPCR mucin Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 7 1 GH18
PUL0471 microarray, qPCR mucin Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 9 3 GH92, GH92, GH92
PUL0472 microarray, qPCR mucin Bacteroides thetaiotaomicron 18996345
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 28 8 GH38, GH92, CBM32, GH2, GH78, CBM67, CE1, GH92, GH92, GH130, GH43_8
PUL0530 microarray, qPCR rhamnogalacturonan Bacteroides thetaiotaomicron 22205877
Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20.
2011 Dec degradation 54 21 PL1, CE8, PL1_2, GH2, GH139, GH106, GH2, GH2, GH137, GH2, CBM57, GH138, GH78, GH141, GH127, GH95, GH105, GH140, GH78, GH33, CBM67, GH28, GH78, CBM67, GH143, GH142, GH43_18, GH43, PL1, CE8, PL1_2
PUL0557 gene deletion mutant and growth assay alpha-mannan Bacteroides thetaiotaomicron 25567280
Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 2015 Jan 8;517(7533):165-169. doi: 10.1038/nature13995.
2015 Jan 8 degradation 13 6 GH97, GH67, GH76, GH92, GH76, GH125
PUL0558 gene deletion mutant and growth assay, growth assay, enzyme activity assay rhamnogalacturonan Bacteroides thetaiotaomicron 28329766
Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. 2017 Apr 6;544(7648):65-70. doi: 10.1038/nature21725. Epub 2017 Mar 22.
2017 Apr 6 degradation 50 20 GH2, GH139, GH106, GH2, GH2, GH2, CBM57, GH137, GH138, GH78, GH141, GH127, GH95, GH105, GH140, CBM67, GH33, GH78, GH28, CBM67, GH78, GH142, GH143, GH43_18, GH43, CE8, PL1_2, PL1
PUL0559 gene deletion mutant and growth assay, growth assay, enzyme activity assay rhamnogalacturonan Bacteroides thetaiotaomicron 28329766
Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. 2017 Apr 6;544(7648):65-70. doi: 10.1038/nature21725. Epub 2017 Mar 22.
2017 Apr 6 degradation 12 5 CBM32, GH43_34, GH43_10, GH97, GH29
PUL0560 microarray, qPCR arabinogalactan Bacteroides thetaiotaomicron 18996345, 22205877
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20.
2008 Nov 13,2011 Dec degradation 30 4 PL27, GH43_24, GH43, GH43_24, GH35, CBM32
PUL0562 microarray, qPCR host glycan, rhamnogalacturonan Bacteroides thetaiotaomicron 18996345, 22205877
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20.
2008 Nov 13,2011 Dec degradation 11 4 CBM32, GH43_34, GH43_10, GH97, GH29
PUL0563 microarray, qPCR arabinogalactan Bacteroides thetaiotaomicron 18996345, 22205877
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20.
2008 Nov 13,2011 Dec degradation 14 7 GH127, GH43, GH43_34, GH154, GH43, GH16, GH43_24, GH43_24, GH145, GH105
PUL0564 microarray, qPCR rhamnogalacturonan Bacteroides thetaiotaomicron 18996345, 22205877
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20.
2008 Nov 13,2011 Dec degradation 39 23 GH106, GH28, GH28, CE12, GH2, GH43, GH43_18, GH42, GH28, CE4, CE0, GH28, GH2, GH27, CBM35, GH35, PL9, PL9_1, PL26, CE12, GH105, PL11, PL11_1, GH105, CE4, CE0, CE6, GH2, PL9_1
PUL0665 UHPLC-MS, RNA-seq, RT-qPCR pectin Bacteroides thetaiotaomicron VPI-5482 34420703
Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism. Carbohydr Polym. 2021 Nov 15;272:118534. doi: 10.1016/j.carbpol.2021.118534. Epub 2021 Aug 6.
2021 Nov 15 degradation 7 1 GH30
PUL0666 UHPLC-MS, RNA-seq, RT-qPCR pectin Bacteroides thetaiotaomicron VPI-5482 34420703
Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism. Carbohydr Polym. 2021 Nov 15;272:118534. doi: 10.1016/j.carbpol.2021.118534. Epub 2021 Aug 6.
2021 Nov 15 degradation 5 4 GH35, GH43, GH51
PUL0667 UHPLC-MS, RNA-seq, RT-qPCR pectin Bacteroides thetaiotaomicron VPI-5482 34420703
Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism. Carbohydr Polym. 2021 Nov 15;272:118534. doi: 10.1016/j.carbpol.2021.118534. Epub 2021 Aug 6.
2021 Nov 15 degradation 4 0 NA
PUL0668 UHPLC-MS, RNA-seq, RT-qPCR pectin Bacteroides thetaiotaomicron VPI-5482 34420703
Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism. Carbohydr Polym. 2021 Nov 15;272:118534. doi: 10.1016/j.carbpol.2021.118534. Epub 2021 Aug 6.
2021 Nov 15 degradation 17 8 GH43, GH28, PL9, PL26, CE12, GH105